GFAP 抗体 (AA 411-422) (HRP)
Quick Overview for GFAP 抗体 (AA 411-422) (HRP) (ABIN1740958)
抗原
See all GFAP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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    - 
                                            抗原表位
- AA 411-422
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                                            特异性
- Detects ~50 kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins.
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            纯化方法
- Protein G Purified
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                                            免疫原
- Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP, 100% identical in rat and mouse
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                                            亚型
- IgG1
 
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                                            应用备注
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                        - WB (1:1000)
- optimal dilutions for assays should be determined by the user.
 
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                                            说明
- 
                        1 μg/ml of ABIN1740958 was sufficient for detection of GFAP in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
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                                            缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C
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                                            储存方法
- Conjugated antibodies should be stored at 4°C
 
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    - GFAP (Glial Fibrillary Acidic Protein (GFAP))
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                                            别名
- GFAP
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                                            背景
- The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia.
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                                            基因ID
- 2670
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                                            NCBI登录号
- NP_001124491
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                                            UniProt
- P14136
 抗原
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