TP53INP1 抗体 (AA 1-14)
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北京 101111
Quick Overview for TP53INP1 抗体 (AA 1-14) (ABIN1737783)
抗原
See all TP53INP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-14
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特异性
- Reacts with human p53DINP1. Cross-reacts with mouse and rat protein.
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纯化方法
- Purified
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免疫原
- Peptide corresponding to aa 1-14 of human p53DINP1. This sequence is identical in p53DINP1 alpha and beta and differs from that of mouse p53DINP1 by one amino acid.
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亚型
- IgG
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应用备注
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB: 1-2 μg/mL
Positive control: Human lung tissue -
限制
- 仅限研究用
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缓冲液
- PBS, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Dilute in PBS or medium which is identical to that used in the assay system.
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储存条件
- -20 °C
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储存方法
- Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
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有效期
- 6 months
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- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
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别名
- p53DINP1
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背景
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Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response.
Tumor protein p53-inducible nuclear protein 1 Stress-induced protein p53-dependent damage-inducible nuclear protein 1, p53DINP1 Gene name: TP53INP1, P53DINP1, SIP -
基因ID
- 94241
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UniProt
- Q96A56
抗原
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