Reacts with human p53DINP1. Cross-reacts with mouse and rat protein.
纯化方法
Purified
免疫原
Peptide corresponding to aa 1-14 of human p53DINP1. This sequence is identical in p53DINP1 alpha and beta and differs from that of mouse p53DINP1 by one amino acid.
Working dilution: Optimal dilutions should be determined by the end user. The following are guidelines only: WB: 1-2 μg/mL
Positive control: Human lung tissue
限制
仅限研究用
缓冲液
PBS, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Dilute in PBS or medium which is identical to that used in the assay system.
储存条件
-20 °C
储存方法
Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
有效期
6 months
抗原
TP53INP1
(Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
别名
p53DINP1
背景
Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response.
Tumor protein p53-inducible nuclear protein 1 Stress-induced protein p53-dependent damage-inducible nuclear protein 1, p53DINP1 Gene name: TP53INP1, P53DINP1, SIP