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NKX6-1 抗体 (Internal Region)

This anti-NKX6-1 antibody is a 兔 多克隆 antibody detecting NKX6-1 in WB, ICC, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN1737379
发货至: 中国

Quick Overview for NKX6-1 抗体 (Internal Region) (ABIN1737379)

抗原

See all NKX6-1 抗体
NKX6-1 (NK6 Homeobox 1 (NKX6-1))

适用

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人, 小鼠

宿主

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  • 17
  • 1
  • 1

克隆类型

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  • 17
多克隆

标记

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This NKX6-1 antibody is un-conjugated

应用范围

  • 32
  • 21
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  • 4
  • 2
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  • 1
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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 6
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    • 4
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    • 2
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    • 1
    • 1
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    AA 50-200, Internal Region

    特异性

    Reacts with human and mouse Nkx6

    交叉反应 (详细)

    1.

    纯化方法

    Antigen affinity purified

    免疫原

    A genomic peptide made to an internal region of the human Nkx6.1 protein (within residues 50-200). [Swiss-Prot P78426]

    亚型

    IgG
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    - IHC - P : 1/50 to 1/100 - WB: 1:100-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, glycerol 30 % , Sodium azide 0.05 %

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

    有效期

    6 months
  • 抗原

    NKX6-1 (NK6 Homeobox 1 (NKX6-1))

    别名

    Nkx6.1

    背景

    NKX6.1 is a bi-functional transcription factor that has effects in both the central nervous system and in the pancreas. It has both expression and repression effects on genes, leading to the proper formation of motoneurons, oligodendrocytes, and insulin-secreting beta cells. It is known to interact with Pax6 and Pdx-1, probably at or near the 60 amino acid homeobox DNA-binding domain.Due to its obvious relationship to beta cells and CNS, NKX6.1 is becoming a more interesting target for therapies in diabetes and certain brain diseases.

    UniProt

    P78426

    途径

    Dopaminergic Neurogenesis, Positive Regulation of Peptide Hormone Secretion
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