NKX6-1 抗体 (Internal Region)
Quick Overview for NKX6-1 抗体 (Internal Region) (ABIN1737379)
抗原
See all NKX6-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-200, Internal Region
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特异性
- Reacts with human and mouse Nkx6
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交叉反应 (详细)
- 1.
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纯化方法
- Antigen affinity purified
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免疫原
- A genomic peptide made to an internal region of the human Nkx6.1 protein (within residues 50-200). [Swiss-Prot P78426]
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亚型
- IgG
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- IHC - P : 1/50 to 1/100 - WB: 1:100-1:2000 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, glycerol 30 % , Sodium azide 0.05 %
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 6 months
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- NKX6-1 (NK6 Homeobox 1 (NKX6-1))
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别名
- Nkx6.1
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背景
- NKX6.1 is a bi-functional transcription factor that has effects in both the central nervous system and in the pancreas. It has both expression and repression effects on genes, leading to the proper formation of motoneurons, oligodendrocytes, and insulin-secreting beta cells. It is known to interact with Pax6 and Pdx-1, probably at or near the 60 amino acid homeobox DNA-binding domain.Due to its obvious relationship to beta cells and CNS, NKX6.1 is becoming a more interesting target for therapies in diabetes and certain brain diseases.
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UniProt
- P78426
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途径
- Dopaminergic Neurogenesis, Positive Regulation of Peptide Hormone Secretion
抗原
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