Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only: WB (2 μg/mL) ICC (10 μg/mL)
限制
仅限研究用
缓冲液
PBS, pH 7.4
注意事项
Dilute in PBS or medium that is identical to that used in the assay system.
储存条件
-20 °C
储存方法
Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
有效期
12 months
抗原
BMF
(Bcl2 Modifying Factor (BMF))
别名
Bmf
背景
In healthy cells, Bmf associates with the dynein light chain 2 component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiating the downstream apoptotic program. Bmf is constitutively expressed in many tissues.