BCL10 抗体 (N-Term)
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Quick Overview for BCL10 抗体 (N-Term) (ABIN1732247)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-19, N-Term
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特异性
- Reacts with human Bcl-10.
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纯化方法
- Purified
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免疫原
- Synthetic peptide corresponding to aa 5-19 (N-terminus ) of human Bcl-10
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亚型
- IgG
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC-P (10 μg/mL) WB(1 μg/mL) ICC(1 μg/mL) -
限制
- 仅限研究用
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缓冲液
- PBS, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Dilute in PBS or medium that is identical to that used in the assay system.
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储存条件
- -20 °C
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储存方法
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
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有效期
- 12 months
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- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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别名
- Bcl-10
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背景
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Overexpression of Bcl10 induces JNK, p38, and NF- B activation. Bcl10 interacts with caspase- 9, enhances pro-caspase-9 processing, and induces apoptosis through caspase-9 activation. Bcl10 exhibits a variety of mutations in MALT lymphoma and in B and T cell lymphomas indicating that it may be commonly involved in the pathogenesis of human tumors. Bcl10 is expressed in many human and murine tissues and cell lines.
B-cell lymphoma/leukemia 10 B-cell CLL/lymphoma 10, Bcl-10 CARD-containing molecule enhancing NF-kappa-B CARD-like apoptotic protein, hCLAP CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER Cellular homolog of vCARMEN, cCARMEN Cellular-E10, c-E10 Mammalian CARD-containing adapter molecule E10, mE10 Gene name: BCL10, CARMEN, CIPER, CLAP, IMD37 -
基因ID
- 8915
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UniProt
- O95999
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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