Arc 抗体 (AA 2-18)
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北京 101111
Quick Overview for Arc 抗体 (AA 2-18) (ABIN1731926)
抗原
See all Arc 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-18
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特异性
- Reacts with the human, mouse, and rat ARC.
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纯化方法
- Purified
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免疫原
- Peptide corresponding to aa 2-18 of human ARC.
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亚型
- IgG
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(2 μg/mL)
Positive control: HeLa cells -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Dilute in PBS or medium that is identical to that used in the assay system.
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储存条件
- -20 °C
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储存方法
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
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有效期
- 12 months
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- Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))
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别名
- ARC
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背景
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A novel CARD domain-containing protein was recently identified and designated ARC (apoptosis repressor with CARD). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The mRNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
Nucleolar protein 3 Apoptosis repressor with CARD Muscle-enriched cytoplasmic protein, Myp Nucleolar protein of 30 kDa, Nop30 Gene name: NOL3, ARC, NOP, FCM, -
基因ID
- 8996
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UniProt
- O60936
抗原
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