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TRF2 抗体 (AA 324-500)

This anti-TRF2 antibody is a 小鼠 单克隆 antibody detecting TRF2 in ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724941
发货至: 中国

Quick Overview for TRF2 抗体 (AA 324-500) (ABIN1724941)

抗原

See all TRF2 (TERF2) 抗体
TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

适用

  • 39
  • 10
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 32
  • 6
  • 2
小鼠

克隆类型

  • 34
  • 6
单克隆

标记

  • 27
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TRF2 antibody is un-conjugated

应用范围

  • 29
  • 18
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  • 7
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  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
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ELISA, Immunohistochemistry (IHC)

克隆位点

3H6B4
  • 抗原表位

    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 324-500

    原理

    TERF2 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Galati, Magdinier, Colasanti, Bauwens, Pinte, Ricordy, Giraud-Panis, Pusch, Savino, Cacchione, Gilson: "TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." in: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).

    Diehl, Idowu, Kimmelshue, York, Jackson-Cook, Turner, Holt, Elmore: "Elevated TRF2 in advanced breast cancers with short telomeres." in: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).

  • 抗原

    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

    别名

    TERF2

    背景

    This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.


    分子量

    55.6 kDa

    UniProt

    Q15554

    途径

    Cell Division Cycle, Telomere Maintenance
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