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beta-2 Microglobulin 抗体 (AA 21-100)

Name: beta-2 Microglobulin 抗体 (AA 21-100)
Brand: antibodies-online
SKU: ABIN1724930
Availability: OutOfStock

Cited in 2+ publications. This 小鼠单克隆 anti-beta-2 Microglobulin antibody (Clone 3G5H8) specifically detects beta-2 Microglobulin in WB, IHC, FACS 和 ELISA. The antibody is reactive with 人 samples.

Western blot analysis using B2M mouse mAb against Hela (1), HEK293 (2), HepG2 (3),RAJI (4), A431 (5) and Jurkat (6) cell lysate. (beta-2 Microglobulin 抗体 (AA 21-100))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (beta-2 Microglobulin 抗体 (AA 21-100))

ELISA

Flow cytometric analysis of A431 cells using B2M mouse mAb (green) and negative control (red). (beta-2 Microglobulin 抗体 (AA 21-100))

FACS

Western blot analysis using B2M mAb against human B2M (AA: 21-100) recombinant protein. (beta-2 Microglobulin 抗体 (AA 21-100))

Western blot analysis using B2M mAb against HEK293 (1) and B2M (AA: 21-100)-hIgGFc transfected HEK293 (2) cell lysate. (beta-2 Microglobulin 抗体 (AA 21-100))

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using B2M mouse mAb with DAB staining. (beta-2 Microglobulin 抗体 (AA 21-100))

IHC

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using B2M mouse mAb with DAB staining. (beta-2 Microglobulin 抗体 (AA 21-100))

IHC

7 images

(2 references)

产品编号 ABIN1724930

发货至: 中国

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Quick Overview for beta-2 Microglobulin 抗体 (AA 21-100) (ABIN1724930)

抗原

See all beta-2 Microglobulin (B2M) 抗体

beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This beta-2 Microglobulin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

克隆位点

3G5H8

Discover our top product B2M Primary Antibody

抗原表位
22

21

15

6

5

5

5

2

2

2

1

1

1

1

1

1
AA 21-100

原理

B2M Antibody

纯化方法

Purified antibody

免疫原

Purified recombinant fragment of human B2M (AA: 21-100) expressed in E. Coli.

亚型

IgG2a
anti-beta-2-Microglobulin (B2M) (AA 1-119) antibody
B2M 适用: 人 WB, IF, ELISA, IHC (p), RNAi, PLA 宿主: 小鼠 Monoclonal 3F9-2C2 unconjugated

anti-beta-2-Microglobulin (B2M) (AA 22-119) antibody
B2M 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A2 unconjugated

anti-beta-2-Microglobulin (B2M) (AA 22-119) antibody
B2M 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-beta-2-Microglobulin (B2M) antibody
B2M 适用: 人, Non-Human Primate WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal B2M-961 unconjugated

anti-beta-2-Microglobulin (B2M) antibody
B2M 适用: 人, Non-Human Primate IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal rB2M-961 unconjugated Recombinant Antibody

anti-beta-2-Microglobulin (B2M) antibody
B2M 适用: 人, Non-Human Primate IHC, StM 宿主: 小鼠 Monoclonal B2M-1118 unconjugated

anti-beta-2-Microglobulin (B2M) antibody
B2M 适用: 人 WB, FACS, ELISA, IP, ICC, IHC (p), RIA 宿主: 小鼠 Monoclonal B2M-01 unconjugated

anti-beta-2-Microglobulin (B2M) antibody (Biotin)
B2M 适用: 人 WB, FACS, ELISA, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal B2M-01 Biotin

anti-beta-2-Microglobulin (B2M) antibody
B2M 适用: 人, Non-Human Primate FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal B2M-961 unconjugated

anti-beta-2-Microglobulin (B2M) (AA 22-119) antibody
B2M 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated

应用备注

ELISA: 1/10000
FCM: 1/200 - 1/400

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Bernal, Ruiz-Cabello, Concha, Paschen, Garrido: "Implication of the ?2-microglobulin gene in the generation of tumor escape phenotypes." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 9, pp. 1359-71, (2012) (PubMed).

Hermansen, Hummelshøj, Lundsgaard, Hornum, Keller, Fleckner, Fox, Poulsen, Jacobsen: "Increased serum ?2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients." in: Lupus, Vol. 21, Issue 10, pp. 1098-104, (2012) (PubMed).
抗原

beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

别名

B2M

背景

This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

分子量

13.7 kDa

基因ID

567

UniProt

P61769

途径

TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process