MEF2A 抗体 (AA 391-497)
Quick Overview for MEF2A 抗体 (AA 391-497) (ABIN1724919)
抗原
See all MEF2A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 391-497
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原理
- MEF2A Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human MEF2A (AA: 391-497) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The effects of myocyte enhancer factor 2A gene on the proliferation, migration and phenotype of vascular smooth muscle cells." in: Cell biochemistry and function, Vol. 30, Issue 2, pp. 108-13, (2012) (PubMed).
: "Association and functional analyses of MEF2A as a susceptibility gene for premature myocardial infarction and coronary artery disease." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 2, pp. 165-72, (2009) (PubMed).
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The effects of myocyte enhancer factor 2A gene on the proliferation, migration and phenotype of vascular smooth muscle cells." in: Cell biochemistry and function, Vol. 30, Issue 2, pp. 108-13, (2012) (PubMed).
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- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
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别名
- MEF2A
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背景
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The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 54.8 kDa
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UniProt
- Q02078
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
抗原
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