Dynamin 1-Like 抗体 (AA 69-213)
Quick Overview for Dynamin 1-Like 抗体 (AA 69-213) (ABIN1724907)
抗原
See all Dynamin 1-Like (DNM1L) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
- 
    - 
                                            抗原表位
- AA 69-213
- 
                                            原理
- DNM1L Antibody
- 
                                            纯化方法
- Ascitic fluid
- 
                                            免疫原
- Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.
- 
                                            亚型
- IgG1
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- 
                        ELISA: 1/10000 FCM: 1/200 - 1/400 ICC: 1/200 - 1/1000 
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            状态
- Liquid
- 
                                            缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 
                                            储存液
- Sodium azide
- 
                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- 4 °C,-20 °C
- 
                                            储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
- 
                                            
- 
    - 
                                            : "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model."    in: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012)         (PubMed).        
 : "Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension." in: Circulation research, Vol. 110, Issue 11, pp. 1484-97, (2012) (PubMed).
 
 
- 
                                            : "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model."    in: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012)         (PubMed).        
- 
    - Dynamin 1-Like (DNM1L)
- 
                                            别名
- DNM1L
- 
                                            背景
- 
                        The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. 
 
- 
                                            分子量
- 81.9 kDa
- 
                                            UniProt
- O00429
 抗原
- 
                    
 
                                     
                                     
                                    