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Dynamin 1-Like 抗体 (AA 69-213)

Cited in 2+ publications. This 小鼠 单克隆 anti-Dynamin 1-Like antibody (Clone 4A4C7) specifically detects Dynamin 1-Like in WB, ELISA, ICC 和 FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1724907
发货至: 中国
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Quick Overview for Dynamin 1-Like 抗体 (AA 69-213) (ABIN1724907)

抗原

See all Dynamin 1-Like (DNM1L) 抗体
Dynamin 1-Like (DNM1L)

适用

  • 70
  • 57
  • 41
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 76
  • 12
小鼠

克隆类型

  • 66
  • 22
单克隆

标记

  • 42
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Dynamin 1-Like antibody is un-conjugated

应用范围

  • 53
  • 32
  • 25
  • 22
  • 18
  • 13
  • 13
  • 10
  • 7
  • 5
  • 3
  • 2
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

4A4C7
  • 抗原表位

    • 33
    • 13
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 69-213

    原理

    DNM1L Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Thomas, Jacobson: "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model." in: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012) (PubMed).

    Marsboom, Toth, Ryan, Hong, Wu, Fang, Thenappan, Piao, Zhang, Pogoriler, Chen, Morrow, Weir, Rehman, Archer: "Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension." in: Circulation research, Vol. 110, Issue 11, pp. 1484-97, (2012) (PubMed).

  • 抗原

    Dynamin 1-Like (DNM1L)

    别名

    DNM1L

    背景

    The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

    分子量

    81.9 kDa

    UniProt

    O00429
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