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IGFBP7 抗体 (AA 52-156)

This anti-IGFBP7 antibody is a 小鼠 单克隆 antibody detecting IGFBP7 in ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1724903
发货至: 中国

Quick Overview for IGFBP7 抗体 (AA 52-156) (ABIN1724903)

抗原

See all IGFBP7 抗体
IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

适用

  • 63
  • 34
  • 26
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 63
  • 8
  • 2
  • 1
  • 1
小鼠

克隆类型

  • 59
  • 13
  • 2
单克隆

标记

  • 40
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IGFBP7 antibody is un-conjugated

应用范围

  • 50
  • 22
  • 22
  • 13
  • 13
  • 13
  • 13
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (IHC)

克隆位点

1D9E7
  • 抗原表位

    • 15
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 52-156

    原理

    IGFBP7 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human IGFBP7 (AA: 52-156) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Evdokimova, Tognon, Benatar, Yang, Krutikov, Pollak, Sorensen, Seth: "IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." in: Science signaling, Vol. 5, Issue 255, pp. ra92, (2012) (PubMed).

  • 抗原

    IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

    别名

    IGFBP7

    背景

    This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).

    分子量

    29.1 kDa

    UniProt

    Q16270

    途径

    Growth Factor Binding
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