SERPINA7 抗体 (AA 168-302)
Quick Overview for SERPINA7 抗体 (AA 168-302) (ABIN1724894)
抗原
See all SERPINA7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 168-302
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原理
- SERPINA7 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human SERPINA7 (AA: 168-302) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Human thyroxine binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern." in: Gene, Vol. 506, Issue 2, pp. 289-94, (2012) (PubMed).
: "Explanation for the high heat stability of thyroxine binding globulin-Chicago." in: Endocrine regulations, Vol. 44, Issue 2, pp. 43-7, (2010) (PubMed).
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Human thyroxine binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern." in: Gene, Vol. 506, Issue 2, pp. 289-94, (2012) (PubMed).
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- SERPINA7 (Serpin Family A Member 7 (SERPINA7))
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别名
- SERPINA7
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背景
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There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
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分子量
- 46.3 kDa
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UniProt
- P05543
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途径
- Hormone Transport
抗原
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