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Dynamin 1-Like 抗体 (AA 69-213)

This anti-Dynamin 1-Like antibody is a 小鼠 单克隆 antibody detecting Dynamin 1-Like in WB, ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724863
发货至: 中国

Quick Overview for Dynamin 1-Like 抗体 (AA 69-213) (ABIN1724863)

抗原

See all Dynamin 1-Like (DNM1L) 抗体
Dynamin 1-Like (DNM1L)

适用

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  • 2
  • 2
  • 1
  • 1
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  • 1

宿主

  • 67
  • 8
小鼠

克隆类型

  • 65
  • 10
单克隆

标记

  • 41
  • 5
  • 4
  • 2
  • 2
  • 2
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  • 1
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This Dynamin 1-Like antibody is un-conjugated

应用范围

  • 40
  • 32
  • 24
  • 13
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  • 10
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  • 6
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  • 3
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

4E11B11
  • 抗原表位

    • 24
    • 11
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 69-213

    原理

    DNM1L Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Thomas, Jacobson: "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model." in: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012) (PubMed).

    Marsboom, Toth, Ryan, Hong, Wu, Fang, Thenappan, Piao, Zhang, Pogoriler, Chen, Morrow, Weir, Rehman, Archer: "Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension." in: Circulation research, Vol. 110, Issue 11, pp. 1484-97, (2012) (PubMed).

  • 抗原

    Dynamin 1-Like (DNM1L)

    别名

    DNM1L

    背景

    The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

    分子量

    81.9 kDa

    UniProt

    O00429
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