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Osteoactivin 抗体 (AA 31-260)

Cited in 2+ publications. The 小鼠 单克隆 anti-Osteoactivin antibody (Clone 7C10E5) (ABIN1724859) specifically detects Osteoactivin in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN1724859
发货至: 中国
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Quick Overview for Osteoactivin 抗体 (AA 31-260) (ABIN1724859)

抗原

See all Osteoactivin (GPNMB) 抗体
Osteoactivin (GPNMB)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Osteoactivin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

7C10E5
  • 抗原表位

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    AA 31-260

    原理

    GPNMB Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Tsui, Chang, Feng, Chang, Juang: "Glycoprotein transmembrane nmb: an androgen-downregulated gene attenuates cell invasion and tumorigenesis in prostate carcinoma cells." in: The Prostate, Vol. 72, Issue 13, pp. 1431-42, (2012) (PubMed).

    Williams, Esmaeli, Soheili, Simantov, Gombos, Bedikian, Hwu: "GPNMB expression in uveal melanoma: a potential for targeted therapy." in: Melanoma research, Vol. 20, Issue 3, pp. 184-90, (2010) (PubMed).

  • 抗原

    Osteoactivin (GPNMB)

    别名

    GPNMB

    背景

    The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    64 kDa

    UniProt

    Q14956
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