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KLF1 抗体 (AA 208-362)

There are 2+ publications for this product available. The 小鼠 单克隆 anti-KLF1 antibody is suitable to detect KLF1 in samples from 人. It has been validated for ELISA, IHC 和 FACS.
产品编号 ABIN1724828
发货至: 中国
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Quick Overview for KLF1 抗体 (AA 208-362) (ABIN1724828)

抗原

See all KLF1 抗体
KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

适用

  • 42
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2

宿主

  • 31
  • 11
  • 1
小鼠

克隆类型

  • 33
  • 11
单克隆

标记

  • 28
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KLF1 antibody is un-conjugated

应用范围

  • 30
  • 23
  • 4
  • 3
  • 1
ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

1B6A3
  • 抗原表位

    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 208-362

    原理

    KLF1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human KLF1 (AA: 208-362) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Alhashem, Vinjamur, Basu, Klingmüller, Gaensler, Lloyd: "Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding." in: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011) (PubMed).

    Zhou, Liu, Sun, Pawlik, Townes: "KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching." in: Nature genetics, Vol. 42, Issue 9, pp. 742-4, (2010) (PubMed).

  • 抗原

    KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

    别名

    KLF1

    背景

    This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.

    分子量

    38.2 kDa

    UniProt

    Q13351
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