GUCY1A1 抗体 (AA 22-214)
Quick Overview for GUCY1A1 抗体 (AA 22-214) (ABIN1724788)
抗原
See all GUCY1A1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 22-214
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原理
- GUCY1A3 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human GUCY1A3 (AA: 22-214) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Soluble guanylyl cyclase ?1 and p53 cytoplasmic sequestration and down-regulation in prostate cancer." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 292-307, (2012) (PubMed).
: "A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 16, Issue 8, pp. 1227-39, (2011) (PubMed).
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: "Soluble guanylyl cyclase ?1 and p53 cytoplasmic sequestration and down-regulation in prostate cancer." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 292-307, (2012) (PubMed).
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- GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))
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别名
- GUCY1A3
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背景
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Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.
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分子量
- 77.5 kDa
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基因ID
- 2982
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途径
- Myometrial Relaxation and Contraction
抗原
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