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PDE1B 抗体 (AA 370-536)

PDE1B 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5C4A3 unconjugated
产品编号 ABIN1724781
发货至: 中国
  • 抗原 See all PDE1B 抗体
    PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
    抗原表位
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 370-536
    适用
    • 37
    • 22
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 34
    • 8
    小鼠
    克隆类型
    • 33
    • 9
    单克隆
    标记
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDE1B antibody is un-conjugated
    应用范围
    • 32
    • 21
    • 12
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    PDE1B Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human PDE1B (AA: 370-536 ) expressed in E. Coli.
    克隆位点
    5C4A3
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Vandeput, Wolda, Krall, Hambleton, Uher, McCaw, Radwanski, Florio, Movsesian: "Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes." in: The Journal of biological chemistry, Vol. 282, Issue 45, pp. 32749-57, (2007) (PubMed).

  • 抗原
    PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
    别名
    PDE1B (PDE1B 产品)
    背景
    The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    分子量
    61.4 kDa
    基因ID
    5153
    UniProt
    Q01064
    途径
    Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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