CBX8 抗体 (AA 17-222)
Quick Overview for CBX8 抗体 (AA 17-222) (ABIN1724766)
抗原
See all CBX8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 17-222
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原理
- CBX8 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CBX8 (AA: 17-222) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
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- CBX8 (Chromobox Homolog 8 (CBX8))
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别名
- CBX8
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背景
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Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.
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分子量
- 43.4 kDa
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基因ID
- 57332
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UniProt
- Q9HC52
抗原
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