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CBX8 抗体 (AA 17-222)

Cited in 1 publication. This 小鼠 单克隆 anti-CBX8 antibody (Clone 9C3D4) specifically detects CBX8 in WB, ELISA 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN1724766
发货至: 中国
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Quick Overview for CBX8 抗体 (AA 17-222) (ABIN1724766)

抗原

See all CBX8 抗体
CBX8 (Chromobox Homolog 8 (CBX8))

适用

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  • 4
  • 2
  • 1
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宿主

  • 50
  • 11
  • 1
小鼠

克隆类型

  • 52
  • 10
单克隆

标记

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  • 2
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This CBX8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

9C3D4
  • 抗原表位

    • 8
    • 8
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    • 4
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    • 1
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    AA 17-222

    原理

    CBX8 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CBX8 (AA: 17-222) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Dietrich, Bracken, Trinh, Schjerling, Koseki, Rappsilber, Helin, Hansen: "Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).

  • 抗原

    CBX8 (Chromobox Homolog 8 (CBX8))

    别名

    CBX8

    背景

    Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.

    分子量

    43.4 kDa

    基因ID

    57332

    UniProt

    Q9HC52
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