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Chromogranin A 抗体 (AA 87-252)

This anti-Chromogranin A antibody is a 小鼠 单克隆 antibody detecting Chromogranin A in FACS, WB, ELISA 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724755
发货至: 中国

Quick Overview for Chromogranin A 抗体 (AA 87-252) (ABIN1724755)

抗原

See all Chromogranin A (CHGA) 抗体
Chromogranin A (CHGA)

适用

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  • 92
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  • 35
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  • 15
  • 6
  • 5
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1

宿主

  • 143
  • 138
  • 5
  • 1
小鼠

克隆类型

  • 177
  • 109
单克隆

标记

  • 121
  • 21
  • 18
  • 15
  • 14
  • 14
  • 14
  • 14
  • 14
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Chromogranin A antibody is un-conjugated

应用范围

  • 141
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  • 60
  • 54
  • 53
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  • 22
  • 14
  • 13
  • 12
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  • 4
  • 3
  • 1
  • 1
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  • 1
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

克隆位点

1A6B6
  • 抗原表位

    • 19
    • 15
    • 7
    • 6
    • 4
    • 4
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    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 87-252

    原理

    CHGA Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CHGA (AA: 87-252 ) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Mergler, Skrzypski, Sassek, Pietrzak, Pucci, Wiedenmann, Strowski: "Thermo-sensitive transient receptor potential vanilloid channel-1 regulates intracellular calcium and triggers chromogranin A secretion in pancreatic neuroendocrine BON-1 tumor cells." in: Cellular signalling, Vol. 24, Issue 1, pp. 233-46, (2011) (PubMed).

    El Ali, Fichna, Piniewska, Kosowicz, Grzymis?awski: "Chromogranin A as a useful neuroendocrine marker in patients with autoimmune Addison's disease." in: Journal of endocrinological investigation, Vol. 33, Issue 3, pp. 186-91, (2010) (PubMed).

  • 抗原

    Chromogranin A (CHGA)

    别名

    CHGA

    背景

    The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.

    分子量

    50.7 kDa

    基因ID

    1113

    UniProt

    P10645

    途径

    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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