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Chromogranin A 抗体 (AA 87-252)

Cited in 2+ publications. This 小鼠 单克隆 anti-Chromogranin A antibody (Clone 1A6B6) specifically detects Chromogranin A in FACS, WB, ELISA 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN1724755
发货至: 中国
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Quick Overview for Chromogranin A 抗体 (AA 87-252) (ABIN1724755)

抗原

See all Chromogranin A (CHGA) 抗体
Chromogranin A (CHGA)

适用

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宿主

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  • 5
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小鼠

克隆类型

  • 166
  • 99
单克隆

标记

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This Chromogranin A antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

克隆位点

1A6B6
  • 抗原表位

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    AA 87-252

    原理

    CHGA Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CHGA (AA: 87-252 ) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Mergler, Skrzypski, Sassek, Pietrzak, Pucci, Wiedenmann, Strowski: "Thermo-sensitive transient receptor potential vanilloid channel-1 regulates intracellular calcium and triggers chromogranin A secretion in pancreatic neuroendocrine BON-1 tumor cells." in: Cellular signalling, Vol. 24, Issue 1, pp. 233-46, (2011) (PubMed).

    El Ali, Fichna, Piniewska, Kosowicz, Grzymis?awski: "Chromogranin A as a useful neuroendocrine marker in patients with autoimmune Addison's disease." in: Journal of endocrinological investigation, Vol. 33, Issue 3, pp. 186-91, (2010) (PubMed).

  • 抗原

    Chromogranin A (CHGA)

    别名

    CHGA

    背景

    The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.

    分子量

    50.7 kDa

    基因ID

    1113

    UniProt

    P10645

    途径

    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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