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BMPR1A 抗体 (AA 179-378)

This anti-BMPR1A antibody is a 小鼠 单克隆 antibody detecting BMPR1A in WB, ELISA, IHC, FACS 和 ICC. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724745
发货至: 中国

Quick Overview for BMPR1A 抗体 (AA 179-378) (ABIN1724745)

抗原

See all BMPR1A 抗体
BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

适用

  • 76
  • 54
  • 36
  • 2
  • 1
人, 小鼠

宿主

  • 96
  • 10
  • 1
小鼠

克隆类型

  • 98
  • 9
单克隆

标记

  • 57
  • 8
  • 7
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BMPR1A antibody is un-conjugated

应用范围

  • 95
  • 55
  • 46
  • 26
  • 14
  • 11
  • 8
  • 6
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

4B7B2
  • 抗原表位

    • 16
    • 10
    • 9
    • 8
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 179-378

    原理

    BMPR1A Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human BMPR1A (AA: 179-378 ) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nickel, Kotzsch, Sebald, Mueller: "Purification, crystallization and preliminary data analysis of the ligand-receptor complex of the growth and differentiation factor 5 variant R57A (GDF5R57A) and BMP receptor IA (BRIA)." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 67, Issue Pt 5, pp. 551-5, (2011) (PubMed).

    Nieminen, Abdel-Rahman, Ristimäki, Lappalainen, Lahermo, Mecklin, Järvinen, Peltomäki: "BMPR1A mutations in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency." in: Gastroenterology, Vol. 141, Issue 1, pp. e23-6, (2011) (PubMed).

  • 抗原

    BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

    别名

    BMPR1A

    背景

    The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

    分子量

    60 kDa

    基因ID

    657

    UniProt

    P36894

    途径

    Stem Cell Maintenance
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