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RUNX3 抗体 (AA 186-252)

RUNX3 适用: 人, 小鼠 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2B3 unconjugated
产品编号 ABIN1724742
发货至: 中国
  • 抗原 See all RUNX3 抗体
    RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
    抗原表位
    • 16
    • 15
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 186-252
    适用
    • 96
    • 30
    • 24
    • 16
    • 14
    • 13
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 83
    • 14
    小鼠
    克隆类型
    • 86
    • 11
    单克隆
    标记
    • 36
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RUNX3 antibody is un-conjugated
    应用范围
    • 83
    • 36
    • 33
    • 25
    • 23
    • 19
    • 13
    • 11
    • 8
    • 6
    • 6
    • 2
    • 2
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    RUNX3 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.
    克隆位点
    2B3
    亚型
    IgG2b
    Top Product
    Discover our top product RUNX3 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Mei, Bai, Liu, Li, Wu, Yu, Zheng: "RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 12, pp. 1823-30, (2011) (PubMed).

  • 抗原
    RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
    别名
    RUNX3 (RUNX3 产品)
    背景
    This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    44.4 kDa
    基因ID
    864
    UniProt
    Q13761
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