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RUNX3 抗体 (AA 186-252)

This anti-RUNX3 antibody is a 小鼠 单克隆 antibody detecting RUNX3 in ELISA, IHC, FACS 和 ICC. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1724742
发货至: 中国

Quick Overview for RUNX3 抗体 (AA 186-252) (ABIN1724742)

抗原

See all RUNX3 抗体
RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

适用

  • 100
  • 33
  • 24
  • 16
  • 14
  • 13
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 89
  • 14
小鼠

克隆类型

  • 92
  • 11
单克隆

标记

  • 41
  • 8
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RUNX3 antibody is un-conjugated

应用范围

  • 89
  • 37
  • 35
  • 26
  • 23
  • 22
  • 13
  • 12
  • 10
  • 7
  • 6
  • 3
  • 2
  • 1
ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

2B3
  • 抗原表位

    • 16
    • 16
    • 9
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 186-252

    原理

    RUNX3 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Mei, Bai, Liu, Li, Wu, Yu, Zheng: "RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 12, pp. 1823-30, (2011) (PubMed).

  • 抗原

    RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

    别名

    RUNX3

    背景

    This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    44.4 kDa

    基因ID

    864

    UniProt

    Q13761
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