GM-CSF 抗体 (AA 18-144)
Quick Overview for GM-CSF 抗体 (AA 18-144) (ABIN1724740)
抗原
See all GM-CSF (CSF2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 18-144
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原理
- CSF2 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human CSF2 (aa18-144) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Association of genetic variations in the CSF2 and CSF3 genes with lung function in smoking-induced COPD." in: The European respiratory journal, Vol. 32, Issue 1, pp. 25-34, (2008) (PubMed).
: "GM-CSF enhances a CpG-independent pathway of neutrophil activation triggered by bacterial DNA." in: Molecular immunology, Vol. 46, Issue 1, pp. 37-44, (2008) (PubMed).
: "The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation." in: Cell, Vol. 134, Issue 3, pp. 496-507, (2008) (PubMed).
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: "Association of genetic variations in the CSF2 and CSF3 genes with lung function in smoking-induced COPD." in: The European respiratory journal, Vol. 32, Issue 1, pp. 25-34, (2008) (PubMed).
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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别名
- CSF2
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背景
- The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.
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分子量
- 16 kDa
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基因ID
- 1437
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UniProt
- P04141
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途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin
抗原
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