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CDC25C 抗体

This anti-CDC25C antibody is a 小鼠 单克隆 antibody detecting CDC25C in WB, ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724739
发货至: 中国

Quick Overview for CDC25C 抗体 (ABIN1724739)

抗原

See all CDC25C 抗体
CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

适用

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宿主

  • 104
  • 15
小鼠

克隆类型

  • 99
  • 20
单克隆

标记

  • 67
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  • 2
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  • 2
  • 1
  • 1
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This CDC25C antibody is un-conjugated

应用范围

  • 94
  • 51
  • 39
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  • 16
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

1F12
  • 原理

    CDC25C Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CDC25C expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Zheng, Kosti, Loffredo, Bowman, Mechanic, Perlmutter, Jones, Shields, Harris: "Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 9, pp. 2199-210, (2010) (PubMed).

    Busch, Barton, Morgenstern, Götz, Günther, Noll, Montenarh: "The G2/M checkpoint phosphatase cdc25C is located within centrosomes." in: The international journal of biochemistry & cell biology, Vol. 39, Issue 9, pp. 1707-13, (2007) (PubMed).

  • 抗原

    CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

    别名

    CDC25C

    背景

    Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

    分子量

    58 kDa

    基因ID

    995

    UniProt

    P30307

    途径

    Cell Division Cycle, M Phase
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