DKK3 抗体
Quick Overview for DKK3 抗体 (ABIN1724727)
抗原
See all DKK3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- DKK3 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human DKK3 expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Overexpression of Dickkopf 3 in hepatoblastomas and hepatocellular carcinomas." in: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 6, pp. 639-46, (2009) (PubMed).
: "Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma." in: The Journal of urology, Vol. 171, Issue 3, pp. 1314-8, (2004) (PubMed).
: "Identification of a novel calreticulin isoform (Crt2) in human and mouse." in: Gene, Vol. 297, Issue 1-2, pp. 151-8, (2002) (PubMed).
: "
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Overexpression of Dickkopf 3 in hepatoblastomas and hepatocellular carcinomas." in: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 6, pp. 639-46, (2009) (PubMed).
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- DKK3
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背景
- Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.
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分子量
- 38 kDa
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基因ID
- 27122
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UniProt
- Q9UBP4
抗原
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