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DKK3 抗体

This anti-DKK3 antibody is a 小鼠 单克隆 antibody detecting DKK3 in WB, ELISA 和 FACS. Suitable for 人 和 猴. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1724727
发货至: 中国

Quick Overview for DKK3 抗体 (ABIN1724727)

抗原

See all DKK3 抗体
DKK3

适用

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人, 猴

宿主

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小鼠

克隆类型

  • 64
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单克隆

标记

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This DKK3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

4G7
  • 原理

    DKK3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human DKK3 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Pei, Kano, Iijima, Morishita, Inadome, Noguchi: "Overexpression of Dickkopf 3 in hepatoblastomas and hepatocellular carcinomas." in: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 6, pp. 639-46, (2009) (PubMed).

    Kurose, Sakaguchi, Nasu, Ebara, Kaku, Kariyama, Arao, Miyazaki, Tsushima, Namba, Kumon, Huh: "Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma." in: The Journal of urology, Vol. 171, Issue 3, pp. 1314-8, (2004) (PubMed).

    Persson, Rosenquist, Sommarin: "Identification of a novel calreticulin isoform (Crt2) in human and mouse." in: Gene, Vol. 297, Issue 1-2, pp. 151-8, (2002) (PubMed).

  • 抗原

    DKK3

    背景

    Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.

    分子量

    38 kDa

    基因ID

    27122

    UniProt

    Q9UBP4
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