TNK1 抗体 (AA 451-560)
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北京 101111
Quick Overview for TNK1 抗体 (AA 451-560) (ABIN1724711)
抗原
See all TNK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 451-560
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原理
- TNK1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of TNK1 (aa451-560) expressed in E. Coli.
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亚型
- IgG1
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anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) antibody
TNK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (AA 256-286) antibodyTNK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3104 unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (AA 256-286) antibodyTNK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (pTyr277) antibodyTNK1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (AA 554-588), (C-Term) antibodyTNK1 适用: 人 WB 宿主: 兔 Polyclonal RB50687 unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (AA 517-566) antibodyTNK1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (Middle Region) antibodyTNK1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Thirty-eight-negative kinase 1 (TNK1) facilitates TNFalpha-induced apoptosis by blocking NF-kappaB activation." in: Oncogene, Vol. 26, Issue 45, pp. 6536-45, (2007) (PubMed).
: "Kos1, a nonreceptor tyrosine kinase that suppresses Ras signaling." in: Oncogene, Vol. 22, Issue 23, pp. 3562-77, (2003) (PubMed).
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: "Thirty-eight-negative kinase 1 (TNK1) facilitates TNFalpha-induced apoptosis by blocking NF-kappaB activation." in: Oncogene, Vol. 26, Issue 45, pp. 6536-45, (2007) (PubMed).
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- TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))
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别名
- TNK1
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背景
- TNK1: tyrosine kinase, non-receptor, 1. TNK1 is a nonreceptor tyrosine kinase(NRPTK). These kinases, like members of the SRC (MIM 190090) and JAK (see MIM 147795) families, mediate intracellular signaling downstream of receptor activation.Tnk1 is a ubiquitously expressed 47- kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.
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基因ID
- 8711
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UniProt
- Q13470
抗原
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