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EhpB1 (AA 19-133) 抗体

适用: 人 IHC, ELISA, WB 宿主: 小鼠 Monoclonal 5F10A4 unconjugated
产品编号 ABIN1724690
发货至: 中国
  • 抗原
    EhpB1
    抗原表位
    AA 19-133
    适用
    宿主
    小鼠
    克隆类型
    单克隆
    应用范围
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of EphB1 (aa19-133) expressed in E. coli.
    克隆位点
    5F10A4
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Huynh-Do, Vindis, Liu, Cerretti, McGrew, Enriquez, Chen, Daniel: "Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis." in: Journal of cell science, Vol. 115, Issue Pt 15, pp. 3073-81, (2002) (PubMed).

    Prevost, Woulfe, Tanaka, Brass: "Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 14, pp. 9219-24, (2002) (PubMed).

  • 抗原
    EhpB1
    背景

    Description: EhpB1: EPH receptor B1. It is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, medate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.

    Aliases: ELK, NET, Hek6, EPHT2, EPHB1

    分子量
    110 kDa
    基因ID
    2047
    HGNC
    2047
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