Quick Overview for EhpB1 (AA 19-133) 抗体 (ABIN1724690)
抗原
EhpB1
适用
人
宿主
小鼠
克隆类型
单克隆
应用范围
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
克隆位点
5F10A4
抗原表位
AA 19-133
原理
EhpB1 Antibody
纯化方法
Ascitic fluid
免疫原
Purified recombinant fragment of EphB1 (aa19-133) expressed in E. Coli.
亚型
IgG1
应用备注
ELISA: 1/10000
限制
仅限研究用
状态
Liquid
缓冲液
Ascitic fluid containing 0.03 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Huynh-Do, Vindis, Liu, Cerretti, McGrew, Enriquez, Chen, Daniel: "Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis." in: Journal of cell science, Vol. 115, Issue Pt 15, pp. 3073-81, (2002) (PubMed).
Prevost, Woulfe, Tanaka, Brass: "Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 14, pp. 9219-24, (2002) (PubMed).
抗原
EhpB1
背景
EhpB1: EPH receptor B1. It is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, medate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.