KAT5 抗体
(2 references)Quick Overview for KAT5 抗体 (ABIN1724672)
抗原
See all KAT5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TIP60 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human TIP60 expressed in E. Coli.
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亚型
- IgG2b
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anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 18-208) antibody
KAT5 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2A11H7 unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 3-512) antibodyKAT5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 1-513) antibodyKAT5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 1-230) antibodyKAT5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 18-208) antibodyKAT5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4B3B4 unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (C-Term) antibodyKAT5 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 山羊, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (pSer86) antibodyKAT5 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 480-530) antibodyKAT5 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 230-462) antibodyKAT5 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) antibodyKAT5 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 3557C4a unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Patterning chromatin: form and function for H2A.Z variant nucleosomes." in: Current opinion in genetics & development, Vol. 16, Issue 2, pp. 119-24, (2006) (PubMed).
: "In and out: histone variant exchange in chromatin." in: Trends in biochemical sciences, Vol. 30, Issue 12, pp. 680-7, (2005) (PubMed).
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: "Patterning chromatin: form and function for H2A.Z variant nucleosomes." in: Current opinion in genetics & development, Vol. 16, Issue 2, pp. 119-24, (2006) (PubMed).
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- KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
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别名
- TIP60
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背景
- HTATIP (HIV-1 Tat interacting protein TIP60, about 60 kDa) belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. In addition to the growing number of post-translational histone modifications regulating chromatin structure, cells can also exchange canonical histones with variant histones that can directly or indirectly modulate chromatin structure. There are five major variants of histone H2A: canonical H2A (most abundant), H2A.X, MacroH2A, H2ABbd and H2A.Z. Histone H2A.Z, the most conserved variant across species, functions as both a positive and negative regulator of transcription and is important for chromosome stability. Several homologous protein complexes, such as SWR-C, TIP60 and SRCAP (mammals), have been shown to catalyze the ATP-dependent exchange of H2A.Z for H2A in the nucleosome. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
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分子量
- 60 kDa
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UniProt
- Q92993
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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