GSTP1 抗体
(2 references)Quick Overview for GSTP1 抗体 (ABIN1724656)
抗原
See all GSTP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- GSTP1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human GSTP1 expressed in E. Coli.
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亚型
- IgG1
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anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) antibody
GSTP1 适用: 人 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 2-210) antibodyGSTP1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1A7B5 unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 97-126) antibodyGSTP1 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB20807 unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) antibodyGSTP1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) antibodyGSTP1 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2G6-F6 unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) antibodyGSTP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 2-210) antibodyGSTP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) antibodyGSTP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (N-Term) antibodyGSTP1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 171-201), (C-Term) antibodyGSTP1 适用: 人 WB, IF, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells." in: Cancer research, Vol. 63, Issue 2, pp. 498-504, (2003) (PubMed).
: "Nrf2 transactivator-independent GSTP1-1 expression in "GSTP1-1 positive" single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells." in: Carcinogenesis, Vol. 23, Issue 3, pp. 457-62, (2002) (PubMed).
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: "Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells." in: Cancer research, Vol. 63, Issue 2, pp. 498-504, (2003) (PubMed).
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- GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
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别名
- GSTP1
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背景
- GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90 % ) of prostate carcinomas and is associated with transcriptional down-regulation.
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分子量
- 23 kDa
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UniProt
- P09211
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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