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SNCA 抗体

SNCA 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 2B2D1 unconjugated
产品编号 ABIN1724652
发货至: 中国
  • 抗原 See all SNCA 抗体
    SNCA (Synuclein, alpha (SNCA))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This SNCA antibody is un-conjugated
    应用范围
    • 210
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    ELISA, Immunohistochemistry (IHC)
    原理
    SNCA Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of SNCA expressed in E. Coli.
    克隆位点
    2B2D1
    亚型
    IgG1
    Top Product
    Discover our top product SNCA Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Li, Lin, Xie, Hu: "The early events of alpha-synuclein oligomerization revealed by photo-induced cross-linking." in: Protein and peptide letters, Vol. 13, Issue 4, pp. 385-90, (2006) (PubMed).

  • 抗原
    SNCA (Synuclein, alpha (SNCA))
    别名
    SNCA (SNCA 产品)
    背景

    Description: Alpha-synuclein (SNCA), with 140-amino acid protein (about 15 kDa), belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Immunohistochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson's disease, Dementia with Lewy bodies and Multiple System Atrophy.

    Aliases: PD1, NACP, PARK1, PARK4, MGC110988

    基因ID
    6622
    HGNC
    6622
    UniProt
    P37840
    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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