SNCA 抗体
Quick Overview for SNCA 抗体 (ABIN1724652)
抗原
See all SNCA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
- 
    - 
                                            原理
- SNCA Antibody
- 
                                            纯化方法
- Ascitic fluid
- 
                                            免疫原
- Purified recombinant fragment of SNCA expressed in E. Coli.
- 
                                            亚型
- IgG1
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- ELISA: 1/10000
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            状态
- Liquid
- 
                                            缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 
                                            储存液
- Sodium azide
- 
                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- 4 °C,-20 °C
- 
                                            储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
- 
                                            
- 
    - 
                                            : "The early events of alpha-synuclein oligomerization revealed by photo-induced cross-linking."    in: Protein and peptide letters, Vol. 13, Issue 4, pp. 385-90, (2006)         (PubMed).        
 
 
- 
                                            : "The early events of alpha-synuclein oligomerization revealed by photo-induced cross-linking."    in: Protein and peptide letters, Vol. 13, Issue 4, pp. 385-90, (2006)         (PubMed).        
- 
    - SNCA (Synuclein, alpha (SNCA))
- 
                                            别名
- SNCA
- 
                                            背景
- Alpha-synuclein (SNCA), with 140-amino acid protein (about 15 kDa), belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Immunohistochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson's disease, Dementia with Lewy bodies and Multiple System Atrophy.
- 
                                            基因ID
- 6622
- 
                                            UniProt
- P37840
- 
                                            途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
 抗原
- 
                    
 
                                     
                                     
                                    