BCL10 抗体
(2 references)Quick Overview for BCL10 抗体 (ABIN1724629)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- BCL-10 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human BCL-10 expressed in E. Coli.
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亚型
- IgG1
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anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 122-168) antibody
BCL10 适用: 人 IHC, IF, FACS, StM 宿主: 兔 Monoclonal BL10-2988R unconjugated Recombinant Antibody
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 122-168) antibodyBCL10 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal BL10-411 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6A8 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 98-234) antibodyBCL10 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3C11F4 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-143) antibodyBCL10 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1185CT13-2-1-2 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-233) antibodyBCL10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 24-51), (N-Term) antibodyBCL10 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB24271 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 4F8 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 27-55), (N-Term) antibodyBCL10 适用: 人, 小鼠 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19012-9, (2001) (PubMed).
: "Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21405-9, (2001) (PubMed).
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: "Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19012-9, (2001) (PubMed).
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- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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别名
- BCL-10
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背景
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Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important
role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other
CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as
upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which
encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to
synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to
the same pathogenetic process that leads to the malignancy. -
分子量
- 26 kDa
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基因ID
- 8915
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NCBI登录号
- NP_003912
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UniProt
- O95999
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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