Tacrolimus (FK506) 抗体
This anti- antibody is a 小鼠 单克隆 antibody detecting in ELISA 和 WB. Suitable for 化学剂.
Quick Overview for Tacrolimus (FK506) 抗体 (ABIN1722861)
抗原
Tacrolimus (FK506)
适用
化学剂
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
克隆位点
FK1
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特异性
- Reacts with conjugated and non-conjugated FK-506 (Kd=10E-9M)
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纯化方法
- Purified
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免疫原
- FK-506 conjugated to bovine serum albumin.
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亚型
- IgM
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应用备注
- Working dilution: Optimal dilution should be determined by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Dilute in PBS or medium which is identical to that used in the assay system.
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储存条件
- -20 °C
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储存方法
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
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有效期
- 12 months
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- Tacrolimus (FK506)
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别名
- FK-506
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物质类
- Chemical
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背景
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FK-506 is a novel macrolide with similar, but more potent, immunosuppressant activity than cyclosporine. FK-506 is used for primary or rescue immunosuppression in patients after solid organ transplantation. Clinically relevant side effects of FK-506 administration are nephrotoxicity, neurotoxicity, diabetes mellitus, and hypertension. Most of these side effects are related to blood levels of FK-506 rather than dosage. Therefore, therapeutic drug monitoring of FK-506 is a prerequisite for therapy. The whole blood target level range aimed for in clinical practice is 3.0-20.0 ng/mL and depends on the patient's liver function, the nature of organ transplantation, and the time after transplantation.
Tacrolimus Fujimycin CAS : 109581-93-3 C44H69NO12 . H2O
抗原
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