TXNDC5 抗体 (AA 52-63)
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北京 101111
Quick Overview for TXNDC5 抗体 (AA 52-63) (ABIN1721515)
抗原
See all TXNDC5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 52-63
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特异性
- Reacts with human EndoPDI.
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纯化方法
- Purified (protein G)
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免疫原
- Synthetic peptide corresponding to aa 52-63 (ADGEDGQDPHSK) of human EndoPDI (accession no. NP_001139021).
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亚型
- IgG2a
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC(1:10 - 1:500) IF(1:10 - 1:500) IHC(1:10 - 1:500) IP(1:10 - 1:500) WB(1 μg/mL)
Positive control: Heat-shocked HeLa cell lysate. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Dilute in PBS or medium which is identical to that used in the assay system.
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储存条件
- -20 °C
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储存方法
- This antibody is stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
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- TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))
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别名
- EndoPDI
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背景
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Endothelial protein disulfide isomerase (EndoPDI) is a thiredoxin member of the protein disulfide isomerase family of chaperones. This enzyme is localized in the endoplasmic reticulum in primary endothelial cells but colocalizes with nucleoli in the nuclei of breast, colon, and kidney cancer cells. EndoPDI mRNA and protein expression is iduced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia.
Thioredoxin domain containing 5 (endoplasmic reticulum) Endoplasmic reticulum resident protein 46, ER protein 46, ERp46 Thioredoxin-like protein p46 HCC2, HCC-2 STRF8 PDIA15 UNQ364 Gene name :TXNDC5 -
基因ID
- 81567
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UniProt
- Q8NBS9
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途径
- Cell RedoxHomeostasis
抗原
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