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Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) 抗体

This anti- antibody is a 小鼠 单克隆 antibody detecting in IHC 和 WB. Suitable for 小鼠, 人 和 大鼠.
产品编号 ABIN1721485
发货至: 中国

Quick Overview for Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) 抗体 (ABIN1721485)

抗原

Cav3.1 Ca2+ Channel

适用

小鼠, 人, 大鼠

宿主

  • 2
小鼠

克隆类型

  • 2
单克隆

标记

  • 2
非结合性

应用范围

  • 2
  • 2
  • 1
Immunohistochemistry (IHC), Western Blotting (WB)

克隆位点

S178A-9
  • 抗原表位

    AA 2052-2172, C-Term

    特异性

    Reacts withhuman, mouse, and rat Cav3.1. Does not cross-react with Cav3.2.

    纯化方法

    Purified

    免疫原

    Fusion protein corresponding to aa 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession no. NP_001106284.1).

    亚型

    IgG1
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB(1 - 2 μg/mL) IHC(1 - 10 μg/mL)

    Positive control: Rat brain membranes

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 50 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Dilute in PBS or medium that is identical to that used in the assay system.

    储存条件

    -20 °C

    储存方法

    Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Cav3.1 Ca2+ Channel

    背景

    Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cav3.1 is a low-voltage activated T-type calcium channel expressed throughout the body. Drugs that block T-type calcium channels are used as antihypertensives and anti-epileptics and possibly in some anesthetics and antipsychotics.

    Voltage-dependent T-type calcium channel subunit alpha-1G Cav3.1c NBR13 Voltage-gated calcium channel subunit alpha Cav3.1 Gene name: CACNA1G, KIAA1123 Ca(V)T.1, Cav3.1, NBR13

    基因ID

    8913

    UniProt

    O43497
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