CD81 抗体
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北京 101111
Quick Overview for CD81 抗体 (ABIN1720914)
抗原
See all CD81 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Anti-human CD81 (TAPA-1)
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产品特性
- Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
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纯化方法
- Protein G
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免疫原
- genetic immunisation with cDNA encoding human CD81
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亚型
- IgG2b
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anti-CD81 (CD81) antibody
KO Validated CD81 适用: 人 FACS, WB, IF, ICC, IHC (p), BP 宿主: 兔 Polyclonal unconjugated
anti-CD81 (CD81) (AA 1-100) antibodyCD81 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD81 (CD81) (AA 190-201), (Extracellular) antibodyCD81 适用: 人 FACS, WB, IHC, LCI 宿主: 兔 Polyclonal unconjugated
anti-CD81 (CD81) antibodyCD81 适用: 人 FACS, WB, IHC, ELISA 宿主: 兔 Monoclonal 9F7 unconjugated Recombinant Antibody
anti-CD81 (CD81) antibodyCD81 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, IF, Func, StM 宿主: 小鼠 Monoclonal 1-3-3-22 unconjugated
anti-CD81 (CD81) antibodyCD81 适用: 人, 小鼠, 大鼠 ELISA, Coat 宿主: 兔 Monoclonal C81-2885R unconjugated Recombinant Antibody
anti-CD81 (CD81) antibodyCD81 适用: 人, 兔, Cat FACS, WB, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal M38 unconjugated
anti-CD81 (CD81) antibody (FITC)CD81 适用: 人, 兔, Cat FACS 宿主: 小鼠 Monoclonal M38 FITC
anti-CD81 (CD81) antibody (PE)CD81 适用: 人, 兔, Cat FACS 宿主: 小鼠 Monoclonal M38 PE
anti-CD81 (CD81) (AA 190-201), (Extracellular) antibody (FITC)CD81 适用: 人 FACS, LCI 宿主: 兔 Polyclonal FITC
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应用备注
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Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. -
说明
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Synonyms: TAPA-1
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限制
- 仅限研究用
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C
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储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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: "A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." in: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).
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: "A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." in: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).
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- CD81
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别名
- CD81
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背景
- CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins. CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry.
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UniProt
- P60033
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途径
- Inositol Metabolic Process, Hepatitis C
抗原
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