VPREB1 抗体 (AA 61-145)
Quick Overview for VPREB1 抗体 (AA 61-145) (ABIN1715058)
抗原
See all VPREB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-145
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human VPREB1/CD179a
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- VPREB1 (Pre-B Lymphocyte 1 (VPREB1))
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别名
- VPREB1/CD179a
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背景
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Synonyms: CD179 antigen like family member A, CD179 antigen-like family member A, CD179a, IGI, IGVPB, Immunoglobulin iota chain, Pre B lymphocyte 1, pre-B lymphocyte 1, Protein VPreB1, VpreB protein, VPREB 1, VPREB, VpreB protein, VPREB_HUMAN, VPREB1.
Background: VpreB is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The gene which encodes VpreB maps to human chromosome 22q11.2. The VpreB and Lambda 5 genes encode the Iota and Omega polypeptide chains, respectively, which associate with the Ig-Mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig gene rearrangements in the early steps of B cell differentiation. In the mouse the two genes are simultaneously expressed in pre-B cells and belong to the same transcription unit. A primary transcript is synthesized from which the pre-B and Lambda 5 mRNAs are derived by alternative splicing. In the human, however, the two genes are separate and do not belong to the same transcription unit.
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基因ID
- 7441
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途径
- Production of Molecular Mediator of Immune Response, Regulation of Cell Size
抗原
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