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FKBP3 抗体 (AA 31-130)

This anti-FKBP3 antibody is a 兔 多克隆 antibody detecting FKBP3 in WB, ELISA, ICC, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1715006
发货至: 中国

Quick Overview for FKBP3 抗体 (AA 31-130) (ABIN1715006)

抗原

See all FKBP3 抗体
FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

适用

  • 36
  • 24
  • 9
  • 6
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  • 4
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  • 3
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 44
  • 3
  • 1
  • 1

克隆类型

  • 46
  • 3
多克隆

标记

  • 32
  • 9
  • 7
  • 1
This FKBP3 antibody is un-conjugated

应用范围

  • 44
  • 25
  • 18
  • 12
  • 11
  • 9
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 31-130

    预测反应

    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FKBP25

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

    别名

    FKBP25

    背景

    Synonyms: FKBP 25, FKBP 3, FKBP25, FKBP3, PPIase, Rotamase, FKBP3_HUMAN.

    Background: FKBP25 is a member of the immunophilin protein family. The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. They inhibit T-cell proliferation by interrupting two specific cytoplasmic signal transmission pathways. FKBP25 is localized in the nucleus and is expressed in the brain, testis, ovary, and spleen. It may influence immunoregulation and cerebellum development, as well as protein folding and trafficking in neurons. FKBP25 associates with transcriptional repressor protein YY1 and histone deaceltylases, HDAC1 and HDAC2. FKBP25 may contain several casein kinase II phosphorylation sites, which are believed to be important for cell growth regulation.

    基因ID

    2287
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