LRRFIP1 抗体 (AA 121-220)
Quick Overview for LRRFIP1 抗体 (AA 121-220) (ABIN1714844)
抗原
See all LRRFIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-220
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LRRFIP1
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亚型
- IgG
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anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (AA 675-784) antibody
LRRFIP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (AA 675-784) antibodyLRRFIP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (AA 675-785) antibodyLRRFIP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (AA 1-315) antibodyLRRFIP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (AA 615-735) antibodyLRRFIP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (AA 1-105) antibodyLRRFIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (AA 1-105) antibodyLRRFIP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (AA 111-160) antibodyLRRFIP1 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 大鼠, 猴, 小鸡, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (AA 520-569) antibodyLRRFIP1 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 大鼠, 小鸡, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (AA 1-105) antibodyLRRFIP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- LRRFIP1 (Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1))
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别名
- LRRFIP1
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背景
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Synonyms: FLAP 1, FLAP1, FLIIAP 1, FLIIAP1, GC binding factor 2, GC-binding factor 2, GCF 2, GCF2, HUFI 1, HUFI1, Leucine rich repeat in FLII interacting protein 1, Leucine rich repeat flightless interacting protein 1, Leucine-rich repeat flightless-interacting protein 1, LRR FLII interacting protein 1, LRR FLII-interacting protein 1, LRRF1_HUMAN, LRRFIP 1, Lrrfip1, MGC10947, MGC119738, MGC119739, NEDD8 conjugating enzyme, TAR RNA interacting protein, TAR RNA-interacting protein, Transcription factor 9 like, TRIP.
Background: LRRFIP1 is an 738 amino acid human protein whose rodent counterpart is known as Lrrfip1 (also designated FLAP in mouse). LRRFIP1 is also believed to control smooth muscle cell proliferation following arterial injury through PDGF-A repression. The N-terminus of LRRFIP1 shows high homology to the coiled-coil domain of FLAP, a protein which binds the leucine-rich repeat (LRR) of Flightless I, and the interaction of LRRFIP1 with the LRR of Flightless I has been confirmed. LRRFIP1 does not bind single-stranded DNA or RNA significantly and binds double-stranded DNA weakly. In contrast, LRRFIP1 binds double-stranded RNA with high affinity, and two molecules of LRRFIP1 bind the TaR stem. The RNA binding domain has been identified and encompasses a lysine-rich motif. Flightless I has a C-terminal TaR-like domain which binds Actin and therefore the association of LRRFIP1 with the LRR of Flightless I may provide a link between the Actin cytoskeleton and RNA in mammalian cells.
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基因ID
- 9208
抗原
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