GLE1 抗体 (AA 611-698)
Quick Overview for GLE1 抗体 (AA 611-698) (ABIN1714807)
抗原
See all GLE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 611-698
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GLE1
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亚型
- IgG
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anti-GLE1 RNA Export Mediator (GLE1) (AA 141-380) antibody
GLE1 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 140-240) antibodyGLE1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 1-698) antibodyGLE1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 218-267) antibodyGLE1 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 1-300) antibodyGLE1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (C-Term) antibodyGLE1 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- GLE1 (GLE1 RNA Export Mediator (GLE1))
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别名
- GLE1
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背景
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Synonyms: GLE 1, GLE1, GLE1 like protein, GLE1 like RNA export mediator, GLE1 RNA export mediator homolog, GLE1 RNA export mediator like yeast, GLE1-like protein, GLE1_HUMAN, GLE1L, hGLE1, LCCS 1, LCCS, LCCS1, Nucleoporin GLE1.
Background: Protein transport across the nucleus is a selective, multi-step process involving several cytoplasmic factors that mediate protein passage through the nuclear pore complex (NPC). Gle1, also known as GLE1L, is a 698 amino acid protein that localizes to both the nucleus and the cytoplasm and belongs to the Gle1 family. Expressed as two alternatively spliced isoforms, Gle1 associates with the NPC and is required for the transport of poly(A)-containing mRNAs from the nucleus to the cytoplasm. Defects in the gene encoding Gle1 are the cause of lethal congenital contracture syndrome type 1 (LCCS1) and lethal arthrogryposis with anterior horn cell disease (LAAHD), the former of which is characterized by early fetal hydrops and akinesia, micrognatia, pulmonary hypoplasia, pterygia and prenatal death, while the latter is associated with respiratory failure.
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基因ID
- 2733
抗原
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