WDFY1 抗体 (AA 21-120)
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北京 101111
Quick Overview for WDFY1 抗体 (AA 21-120) (ABIN1714756)
抗原
See all WDFY1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human WDFY1
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亚型
- IgG
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anti-WD Repeat and FYVE Domain Containing 1 (WDFY1) (AA 261-357) antibody
WDFY1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat and FYVE Domain Containing 1 (WDFY1) (N-Term) antibodyWDFY1 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, 小鸡 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat and FYVE Domain Containing 1 (WDFY1) (AA 42-91) antibodyWDFY1 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, 兔, 小鸡, Bat WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat and FYVE Domain Containing 1 (WDFY1) (N-Term) antibodyWDFY1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- WDFY1 (WD Repeat and FYVE Domain Containing 1 (WDFY1))
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别名
- WDFY1 + WDFY2
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背景
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Synonyms: FENS 1, FENS-1, FENS1, KIAA1435, Phosphoinositide binding protein 1, Phosphoinositide binding protein SR1, Phosphoinositide-binding protein 1, WD repeat and FYVE domain containing 1, WD repeat and FYVE domain-containing protein 1, WD40 and FYVE domain containing protein 1, WD40- and FYVE domain-containing protein 1, WDF1, WDFY1, WDFY1_HUMAN, ZFYVE17, Zinc finger FYVE domain containing protein 17, Zinc finger FYVE domain-containing protein 17, WDFY2, WD repeat and FYVE domain-containing protein 2, Propeller-FYVE protein, WD40- and FYVE domain-containing protein 2, Zinc finger FYVE domain-containing protein 22, WDF2, ZFYVE22
Background: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDFY1 positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. WDFY1 Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines. WDFY2 acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2. WDFY2 positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1
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基因ID
- 57590, 115825
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UniProt
- Q8IWB7, Q96P53
抗原
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