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Glycogen Synthase 1 抗体 (pSer645)

GYS1 适用: 大鼠, 犬 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1714645
发货至: 中国
  • 抗原 See all Glycogen Synthase 1 (GYS1) 抗体
    Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))
    抗原表位
    • 15
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer645
    适用
    • 59
    • 35
    • 28
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    大鼠, 犬
    宿主
    • 58
    • 1
    克隆类型
    • 45
    • 14
    多克隆
    标记
    • 38
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This Glycogen Synthase 1 antibody is un-conjugated
    应用范围
    • 38
    • 25
    • 13
    • 10
    • 9
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    犬, 大鼠
    预测反应
    Human,Mouse,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human Glycogen synthase 1 around the phosphorylation site of Ser645
    亚型
    IgG
    Top Product
    Discover our top product GYS1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))
    别名
    Glycogen synthase 1 (GYS1 产品)
    别名
    GSY antibody, GYS antibody, GYS1 antibody, zgc:63701 antibody, GYS2 antibody, Gys3 antibody, MGS antibody, glycogen synthase 1 antibody, glycogen synthase 1 (muscle) antibody, glycogen synthase 1, muscle antibody, GYS1 antibody, gys1 antibody, Gys1 antibody
    背景

    Synonyms: Glycogen synthase 1 phospho S645, Glycogen synthase 1 phospho Ser645, p-Glycogen synthase 1 S645, Glycogen synthase 1 muscle, Glycogen synthase 1, GSY, GYS, GYS1, EC 2.4.1.11, Glycogen synthase1, GYS 1, Starchsynthase muscle, UDP glucose glycogen glucosyltransferase, GYS1_HUMAN, Glycogen [starch] synthase, muscl.

    Background: Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70 % identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.

    途径
    PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process
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