Glycogen Synthase 1 抗体 (pSer645)
Quick Overview for Glycogen Synthase 1 抗体 (pSer645) (ABIN1714645)
抗原
See all Glycogen Synthase 1 (GYS1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer645
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交叉反应
- 犬, 大鼠
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预测反应
- Human,Mouse,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human Glycogen synthase 1 around the phosphorylation site of Ser645
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亚型
- IgG
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anti-Glycogen Synthase 1 (Muscle) (GYS1) (AA 488-737) antibody
GYS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) antibodyGYS1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer641) antibodyGYS1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 10C1 unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer645) antibodyGYS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) antibodyGYS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (C-Term) antibodyGYS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer641) antibodyGYS1 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 1D1 unconjugated Recombinant Antibody
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer641) antibodyGYS1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer641) antibodyGYS1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer645) antibodyGYS1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))
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别名
- Glycogen synthase 1
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背景
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Synonyms: Glycogen synthase 1 phospho S645, Glycogen synthase 1 phospho Ser645, p-Glycogen synthase 1 S645, Glycogen synthase 1 muscle, Glycogen synthase 1, GSY, GYS, GYS1, EC 2.4.1.11, Glycogen synthase1, GYS 1, Starchsynthase muscle, UDP glucose glycogen glucosyltransferase, GYS1_HUMAN, Glycogen [starch] synthase, muscl.
Background: Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70 % identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.
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途径
- PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process
抗原
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