CXCR4 抗体 (pSer339)
Quick Overview for CXCR4 抗体 (pSer339) (ABIN1714582)
抗原
See all CXCR4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer339
-
交叉反应
- 人, 小鼠
-
预测反应
- Rat,Dog,Cow,Horse,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic phosphopeptide derived from human CXCR4 around the phosphorylation site of Ser339 [HS(p-S)VS]
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
-
别名
- CXCR4
-
背景
-
Synonyms: p-CXCR4 phospho S339, p-CD184 phospho S339, C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Stromal cell-derived factor 1 receptor, SDF-1 receptor, Fusin, Leukocyte-derived seven transmembrane domain receptor, LESTR, CD184 antigen, CXCR4_HUMAN.
Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Monomer. Can form dimers.
-
基因ID
- 55038
-
途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
-