PIP5KL1 抗体 (AA 101-220)
Quick Overview for PIP5KL1 抗体 (AA 101-220) (ABIN1714568)
抗原
See all PIP5KL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-220
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PIP5KL1/PIPKH
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PIP5KL1 (Phosphatidylinositol-4-Phosphate 5-Kinase-Like 1 (PIP5KL1))
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别名
- PIP5KL1
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背景
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Synonyms: bA203J24.5, EC 2.7.1.68, MGC46424, phosphatidylinositol 4 phosphate 5 kinase like 1, phosphatidylinositol phosphate kinase homolog, Phosphatidylinositol-4-phosphate 5-kinase-like protein 1, PI4P 5 kinase like protein 1, PI4P 5-kinase-like protein 1, PI5L1_HUMAN, PIP5KL1, PIPKH, PtdIns4P 5 kinase like protein 1, PtdIns4P-5-kinase-like protein 1.
Background: PIPKH, also known as PIP5KL1 (phosphatidylinositol-4-phosphate 5-kinase-like 1), is a 394 amino acid phosphoinositide kinase-like protein that contains one PIPK domain. Although PIPKH lacks intrinsic lipid kinase activity, it associates with type I PIPKs and may play a role in localization of PIPK activity. Encoded by a gene that maps to human chromosome 9q34.11, PIPKH localizes to cytoplasm, specifically to large cytoplasmic vesicular structures, and exists as two alternatively spliced isoforms. Highly expressed in brain and testis, PIPKH is also expressed at very low levels in heart, spleen, lung, liver, skeletal muscle and kidney. PIPKH heterodimerizes with other type I phosphatidylinositol-4-phosphate 5-kinases, and may function as a scaffold to localize and regulate kinases to specific cell compartments. Overexpression of PIPKH may suppress cell proliferation and migration in human gastric cancer cells and may also inhibit cervical cancer formation.
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基因ID
- 138429
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途径
- Inositol Metabolic Process
抗原
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