BAMBI 抗体 (AA 101-200)
(3 references)Quick Overview for BAMBI 抗体 (AA 101-200) (ABIN1714490)
抗原
See all BAMBI 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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交叉反应
- 人, 小鼠, Pig, 大鼠
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预测反应
- Dog,Cow,Sheep,Rabbit,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human BAMBI
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亚型
- IgG
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anti-BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) (AA 1-260) antibody
BAMBI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C1-1D1 unconjugated
anti-BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) (AA 21-152) antibodyBAMBI 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) (AA 29-130) antibodyBAMBI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia." in: Scientific reports, Vol. 6, pp. 27051, (2016) (PubMed).
: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." in: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, (2016) (PubMed).
: "Identification and expression analyses of BAMBI mediated by FSH in swine luteinizing granulosa cells." in: Theriogenology, Vol. 82, Issue 8, pp. 1094-101, (2014) (PubMed).
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: "LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia." in: Scientific reports, Vol. 6, pp. 27051, (2016) (PubMed).
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- BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))
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别名
- BAMBI
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背景
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Synonyms: NMA, BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein NMA, BAMBI
Background: BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
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基因ID
- 25805
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UniProt
- Q13145
抗原
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