DAPP1 抗体 (AA 51-160)
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北京 101111
Quick Overview for DAPP1 抗体 (AA 51-160) (ABIN1714433)
抗原
See all DAPP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-160
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原理
- DAPP1 Polyclonal Antibody
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Sheep,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DAPP1/BAM32
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亚型
- IgG
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应用备注
- WB(1:300-5000),
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- DAPP1 (Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1))
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别名
- DAPP1
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背景
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Synonyms: B cell adapter molecule of 32 kDa, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32 kDa, BAM32, DAPP1, DAPP1_HUMAN, DKFZp667E0716, Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, Dual adaptor of phosphotyrosine and 3 phosphoinositides, hDAPP1.
Background: B cell adapter molecule is also designated dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC g2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation. BAM32, which contains one PH domain and one SH2 domain, is primarily expressed in placenta and lung tissues, but can also be detected in heart, liver, pancreas and brain.
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基因ID
- 27071
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途径
- BCR Signaling
抗原
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