FAM134B 抗体 (AA 210-310)
Quick Overview for FAM134B 抗体 (AA 210-310) (ABIN1714363)
抗原
See all FAM134B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 210-310
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特异性
- There is a chance that this protein will cross-react with MSL2 based on a 73 % non-sequential sequence similarity.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FAM134B
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))
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别名
- FAM134B
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背景
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Synonyms: JK1, JK-1, Reticulophagy receptor FAM134B, FAM134B
Background: Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).
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基因ID
- 54463
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UniProt
- Q9H6L5
抗原
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