DMWD 抗体 (AA 501-600)
Quick Overview for DMWD 抗体 (AA 501-600) (ABIN1714355)
抗原
See all DMWD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-600
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预测反应
- Human,Mouse,Rat,Cow
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DMWD/DMRN9
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- DMWD (Dystrophia Myotonica, WD Repeat Containing (DMWD))
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别名
- DMWD/DMRN9
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背景
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Synonyms: dystrophia myotonica containing WD repeat mot,D19S593E, DM 9, DM9, DMR N9, DMR N9 protein, DMRN 9, DMRN9, DMWD, DMWD_HUMAN, Dystrophia myotonica containing WD repeat mot, Dystrophia myotonica containing WD repeat mot protein, Dystrophia myotonica WD repeat containing protein, Dystrophia myotonica WD repeat-containing protein, Dystrophia myotonica-containing WD repeat mot protein, Gene59, Protein 59, Protein DMR-N9.
Background: DMWD is a 674 amino acid protein containing five WD repeats. DMWD may play a role in the development of mental symptoms in severe cases of myotonic dystrophy, a chronic multisystemic disease characterized by wasting of the muscles, heart conduction defects, cataracts, endocrine changes and myotonia. The DMWD gene is located upstream of the DMPK gene and is prominently expressed in tissues affected in myotonic dystrophy patients. DMWD may also contribute to regulation in meiosis. DMWD is expressed in kidney and spleen, with strongest expression in brain, liver and testis. The gene encoding DMWD maps to human chromosome 19q13.32 and mouse chromosome 7 A3.
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基因ID
- 1762
抗原
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