ARIH2 抗体 (AA 41-140)
Quick Overview for ARIH2 抗体 (AA 41-140) (ABIN1714290)
抗原
See all ARIH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-140
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预测反应
- Human,Mouse,Rat,Cow,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ARIH2
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ARIH2 (protein ariadne-2 homolog (ARIH2))
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别名
- ARIH2
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背景
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Synonyms: all trans retinoic acid inducible RING finger, Ari 2, Ari-2, ARI2, ARI2_HUMAN, Ariadne 2, Ariadne 2 protein homolog, ariadne homolog 2 Drosophila, ariadne homolog 2, ARIH 2, Arih2, E3 ubiquitin protein ligase ARIH2, E3 ubiquitin-protein ligase ARIH2, HT005, protein ariadne 2 homolog, Protein ariadne-2 homolog, Triad 1, TRIAD1, Triad1 protein, UIP48.
Background: TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
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基因ID
- 10425
抗原
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