LSD1 抗体 (AA 301-400)
Quick Overview for LSD1 抗体 (AA 301-400) (ABIN1714208)
抗原
See all LSD1 (KDM1A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KDM1
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
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别名
- KDM1
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背景
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Synonyms: Amine oxidase flavin containing domain 2, Amine oxidase flavin containing domain 2, Amine oxidase flavin containing domain protein 2, AOF 2, AOF2, BHC110, BRAF35 HDAC complex protein BHC110, BRAF35-HDAC complex protein BHC110, FAD binding protein BRAF35 HDAC complex, 110 kDa subunit, Flavin containing amine oxidase domain containing protein 2, Flavin-containing amine oxidase domain-containing protein 2, KDM 1, Kdm1a, KDM1A_HUMAN, KIAA0601, LSD 1, LSD1, Lysine K specic demethylase 1, Lysine K specic demethylase 1A, Lysine specic histone demethylase 1, Lysine specic histone demethylase 1A, Lysine-specic histone demethylase 1, Lysine-specic histone demethylase 1A.
Background: Gene activation and repression is specifically regulated by histone methylation status at distinct lysine residues. Lysine specific demethylase 1 (KDM1/LSD1) is a long-sought histone demethylase that specifically demethylates mono and di methyl histone H3 at K4 and K9. Thus KDM1 is a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect
抗原
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